Folate or Folic Acid?

It's important to note that folic acid is a synthetic form of folate, and the two terms are often used interchangeably.

Folate can be found naturally in fruits, legumes, and vegetables, or as a synthetic form called folic acid, which is added to some supplements or fortified foods like enriched flour, pasta, rice, cereal, and bread.

It is estimated that 35% of adults in America use supplements that contain folic acid. However, unmetabolized folic acid can remain in the bloodstream and lead to health issues, including cancer. People who have multiple mutations of MTHFR gene are at a higher risk of toxic build-up, which can cause high homocysteine levels. This, in turn, can block the body's methylation pathways. It is believed that 30% to 50% of the population may carry this gene, and 10% to 20% have the more severe mutation.

The MTHFR genes are responsible for producing enzymes that help in converting homocysteine into methionine, which is a type of amino acid. In case we lack this enzyme, it can severely impact our body's terrain, leading to a rise in homocysteine levels, which further causes inflammation. Even if an individual does not have this mutation, they can still be at risk of nutrient deficiencies, especially those related to folate and B vitamins, particularly (B6, B9 and B12). (B9 or MTHF ) can bypass the methylation process and be absorbed directly. Making it by far the best form of folate.

Homocysteine levels can also rise from smoking, disease, meds, drugs, poor diet, laxatives, alcoholism, etc.

B9 or MTHF can by pass the methylation process and be absorbed directly

Foods enriched with folic acid are labeled as “Enrichment.” To avoid consumption, one can opt for organic produce, homemade meals, and read the labels.

Moms-to-be should be cautious of taking supplements, especially prenatal ones. Ensure that the supplement has folate instead of synthetic folic acid.